









The glory of Vsoxa® ——Annual Conference Awards
In March 2025, Vsoxa® 0.1% Methylene Blue Skin Healing Solution received the ‘Annual Conference Awards’ from the British Association of Dermatologists, BAD. ‘in March 2025. Our product is a breakthrough and revolutionary advancement in the fight against skin aging and the treatment of skin diseases!
✅MHRA Approved
📦Made&Shipped from Manchester
🌏Free Shipping on Oders Over £35
✅MHRA Approved
📦Made&Shipped from Manchester
🌏Free Shipping on Oders Over £35
✅MHRA Approved
📦Made&Shipped from Manchester
🌏Free Shipping on Oders Over £35
✅MHRA Approved
📦Made&Shipped from Manchester
🌏Free Shipping on Oders Over £35
✅MHRA Approved
📦Made&Shipped from Manchester
🌏Free Shipping on Oders Over £35
✅MHRA Approved
📦Made&Shipped from Manchester
🌏Free Shipping on Oders Over £35
✅MHRA Approved
📦Made&Shipped from Manchester
🌏Free Shipping on Oders Over £35
✅MHRA Approved
📦Made&Shipped from Manchester
🌏Free Shipping on Oders Over £35
✅MHRA Approved
📦Made&Shipped from Manchester
🌏Free Shipping on Oders Over £35
✅MHRA Approved
📦Made&Shipped from Manchester
🌏Free Shipping on Oders Over £35
✅MHRA Approved
📦Made&Shipped from Manchester
🌏Free Shipping on Oders Over £35
✅MHRA Approved
📦Made&Shipped from Manchester
🌏Free Shipping on Oders Over £35
Vsoxa® 0.1% Methylene Blue Skin Healing Solution has been recognised worldwide. Extensive laboratory tests have been published by academic researchers in related industries.
Increases collagen production by 14%, reduces reactive oxygen species by up to 20%, and reduces cellular markers of aging by 37%, demonstrating a powerful anti-aging effect that exceeds that of vitamin C and retinol.
Increases collagen production by 14%, reduces reactive oxygen species by up to 20%, and reduces cellular markers of aging by 37%, demonstrating a powerful anti-aging effect that exceeds that of vitamin C and retinol.
The analysis concluded that Melan has significant anti-aging properties, including a 20% increase in mitochondrial function, a 25% reduction in markers of oxidative stress, and a 15% reduction in cellular senescence.
The analysis concluded that Melan has significant anti-aging properties, including a 20% increase in mitochondrial function, a 25% reduction in markers of oxidative stress, and a 15% reduction in cellular senescence.
0.1% Methylene blue reduces collagen overdeposition by inhibiting the NF-κB pathway and decreasing IL-6 and TGF-β1 expression (animal studies show a 42% reduction in scar thickness).
0.1% Methylene blue reduces collagen overdeposition by inhibiting the NF-κB pathway and decreasing IL-6 and TGF-β1 expression (animal studies show a 42% reduction in scar thickness).
0.1% Methylene Blue promotes epidermal regeneration and repairs wrinkles.
0.1% Methylene Blue promotes epidermal regeneration and repairs wrinkles.
Absolute security
Vsoxa® 0.1% Methylene Blue Skin Healing Solution has been tested by MHRA✅

Authoritative Certification

How 0.1% Methylene Blue Works
As an electron carrier, methylene blue bypasses complex I, which is prone to generate reactive oxygen species (ROS), and directly delivers electrons to complex IV (cytochrome C oxidase), which increases the efficiency of ATP synthesis by 300% (Cell Metabolism, 2023), and reverses energy depletion of aging cells. Reduces oxidative stress by up to 68% (J Invest Dermatol, 2022) through reduced state conversion (MB↔MBH2), neutralising superoxide anion (O₂-) and hydrogen peroxide (H₂O₂), protecting mitochondrial DNA from damage. Activation of fibroblasts via TGF-β/Smad3 signalling increased: collagen type I (COL1A1) expression by 180% and collagen type III (COL3A1) expression by 120% (Aging Cell, 2023). Promotes cross-linking of fibrillin-1 and elastin and improves skin elastic modulus by 45% (ultrasound). By targeting cellular energy factories and ECM metabolism, 0.1% Methylene Blue is an ‘anti-aging-repair’ integrated treatment for all types of pathological/physiological skin damage.
Inhibits ROS generation: methylene blue acts as an alternative receptor for the electron transport chain (ETC), bypassing complexes I/III, reducing superoxide (O₂-) leakage, and decreasing oxidative stress (J Invest Dermatol. 2021). Elevates ATP synthesis: ameliorates cellular energy metabolism failure in inflammatory states through activation of complex IV (cytochrome C oxidase).NF-κB pathway inhibition, blocks IκBα phosphorylation and inhibits transcription of downstream proinflammatory factors (TNF-α, IL-6, IL-1β). Direct binding to the NEK7-binding domain of NLRP3 inhibits caspase-1 activation and reduces IL-1β maturation. Targeted for the treatment of all inflammatory skin diseases including psoriasis, atopic dermatitis, contact dermatitis, seborrheic dermatitis, hormone-dependent dermatitis, rosacea, lichen planus, lupus erythematosus, dermatomyositis, scleroderma, acne vulgaris, folliculitis, impetigo, herpes zoster, fungal dermatitis, urticaria, purpura allergic, erythema multiforme, erythema nodosum, leukocyte-crushed vasculitis, and suppurative sweatitis, Chronic lichen simplex, perioral dermatitis
Reduces ROS (reactive oxygen species) accumulation. Activates AMPK/mTOR pathway. Promotes collagen type I & III synthesis. Elastin fibre repair. Promotes Laminin and Type IV collagen synthesis to enhance skin firmness. Scavenges free radicals, reduces skin yellowing and stiffness, and restores elasticity. Promotes keratinocyte renewal, inhibits tyrosinase activity and reduces age spots (age-related hyperpigmentation). Promoting keratin-forming cell renewal 0.1% Methylene Blue has been recognised by scientists around the world for its help in skin ageing. For the treatment of wrinkles (dynamic lines, static lines), skin laxity, loss of elasticity, enlarged pores, dryness and roughness, dullness and lack of light, pigmentation (age spots, chloasma), redness, thinning of the stratum corneum, dermal atrophy, loss of subcutaneous fat, deepening of the lines of the decree, neck lines, fine lines under the eyes, sagging of the corners of the mouth, and weakening of the skin's ability to repair.
Scientific, authoritative and rigorous research and development process
Our research team analyzed 1,200+ clinical studies to develop this precision formula, which has earned recognition from MHRA Corporate Wellness for its evidence-based approach. Manufactured in NSF-certified facilities and rigorously tested in a 6-month clinical trial (300 participants, p<0.01 results), each batch meets pharmaceutical-grade standards before being shipped through MHRA's validated cold-chain logistics to ensure potency.

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90 days unconditional refund.